Six Senses Rome occupies Palazzo Salviati Cesi Mellini, steps from the Pantheon, restored around the remains of a 4th-century church discovered during the works. The materials are all Roman — travertine, lime plaster, cocciopesto.
The spa is built on Roman bathing culture, with a proper caldarium, tepidarium and frigidarium sequence, a Bioarchitecture-led design, and programmes covering detox, sleep, female health and longevity. It is the most convincing marriage of a city hotel and a bathhouse in Europe.


A three, five or seven-day programme at Six Senses Rome addressing hormonal health, cycle and life-stage changes — subjects that most hotel spas skirt entirely.
A wellness consultation and screening establish where you are, then the programme combines targeted treatments, the Roman bathing circuit, nutritional guidance, movement and sleep work, with practitioners who understand hormonal physiology rather than treating it as a footnote.
Women at any stage — cycle, perimenopause, postpartum — who want their physiology taken seriously in a setting that is also a pleasure to be in.
A thoughtfully curated collection of experiences designed to enrich your stay. From wellness and nature to culture and gastronomy, each moment invites you to slow down, reconnect, and immerse yourself in the essence of the estate.